Acute isovolemic hemodilution and blood transfusion

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Isovolemic Hemodilution in Rabbits

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Tolerance to acute isovolemic hemodilution. Effect of anesthetic depth.

BACKGROUND Acceptance of a lower transfusion trigger in the perioperative period requires study of the effects of anesthetic depth on the tolerance to acute isovolemic anemia. Anesthetic agents with negative effects on the cardiovascular system may exert proportionately greater depressant effects on cardiac output response than on tissue oxygen demand, reducing tolerance to acute isovolemic ane...

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Autoregulatory capacity and the effect of isovolemic hemodilution on local cerebral blood flow.

The effect of isovolemic hemodilution with dextran 40 on local cerebral blood flow was measured in eight cats by means of the hydrogen clearance technique. Under normotension the decrease of hematocrit from 35% to 25% causes a sudden increase of up to 30% in local cerebral blood flow. After lowering the mean arterial blood pressure from 140 to 80 mm Hg, hemodilution did not alter cerebral blood...

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Acute effects of isovolemic hemodilution with crystalloids in a canine model of focal cerebral ischemia.

We used 44 splenectomized dogs to study the effects of isovolemic hemodilution with a crystalloid solution. The dogs were randomly divided into a hemodilution and a control group. In each group, 17 dogs were subjected to 6 hours of internal carotid and middle cerebral artery occlusion, and five dogs received sham operations. Isovolemic hemodilution by phlebotomy and Ringer's lactate infusion wa...

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Subcutaneous perfusion and oxygen during acute severe isovolemic hemodilution in healthy volunteers.

HYPOTHESIS Acute severe isovolemic anemia (to a hemoglobin [Hb] concentration of 50 g/L) does not decrease subcutaneous wound tissue oxygen tension (PsqO(2)). SETTING University hospital operating room and inpatient general clinical research center ward. SUBJECTS Twenty-five healthy, paid volunteers. METHODS Subcutaneous oxygen tension and subcutaneous temperature (Tsq) were measured cont...

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ژورنال

عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery

سال: 1993

ISSN: 0022-5223

DOI: 10.1016/s0022-5223(19)34196-0